Donor Semen Insemination

Donor Semen Insemination (also known as therapeutic donor insemination, TDI) is an assisted reproductive technique (ART) where donor sperm is used to achieve pregnancy through intrauterine insemination (IUI) or in vitro fertilization (IVF). This method provides a solution for couples or individuals facing male infertility, genetic conditions, or the absence of a male partner.

Who Can Benefit from Donor Semen Insemination?

This program is recommended for:

• Men with severe male factor infertility (low sperm count, poor motility, azoospermia)
• Men with genetic disorders they do not want to pass on
• Women in same-sex relationships or single women who wish to conceive
• Men with ejaculatory dysfunction or other medical conditions affecting sperm quality
• Couples with previous failed ICSI/IVF cycles due to poor sperm quality

How Does the Donor Semen Process Work?

1. Selection of a Sperm Donor

   • Donors are typically healthy men aged 21-40
   • Undergo comprehensive medical, genetic, and infectious disease screening
   • Donor selection is based on physical traits, ethnicity, blood type, and medical history
   • The recipient can choose an anonymous or known donor

2. Sperm Freezing & Quarantine

   • Donor sperm is collected, processed, and frozen using cryopreservation
   • A 6-month quarantine ensures the sample is free from infectious diseases

3. Fertility Treatment Options

   • Intrauterine Insemination (IUI): Donor sperm is directly inserted into the uterus during ovulation
   • In Vitro Fertilization (IVF): Donor sperm is used to fertilize eggs in a lab, and an embryo is transferred to the uterus

4. Pregnancy Test & Follow-Up

   • A blood test (Beta hCG) is done 10–14 days after insemination to confirm pregnancy
   • If successful, the pregnancy progresses like any natural conception

Success Rates of Donor Semen Insemination

• IUI with donor sperm: Pregnancy rates are 15–25% per cycle, increasing with multiple cycles
• IVF with donor sperm: Success rates range from 50–70% per cycle, depending on egg quality

Benefits of Donor Semen Insemination

✅ Simple & Non-Invasive: IUI is a quick, painless procedure with minimal discomfort
✅ Higher Pregnancy Success: Compared to treatments for severe male infertility
✅ Genetically Healthy Sperm: Donors undergo rigorous genetic and medical screening
✅ Option for IVF/ICSI: Donor sperm can be used in advanced fertility treatments
✅ Safe & Regulated Process: Legal and ethical guidelines ensure safety for intended parents

Considerations & Emotional Aspects

• Psychological counseling is recommended to help with the emotional and ethical aspects
• Some couples may struggle with the lack of genetic connection to the child
• Legal regulations regarding donor anonymity and parental rights vary by country

Conclusion

Donor Semen Insemination is a safe and effective fertility solution for individuals and couples facing male infertility or genetic concerns. With a high success rate and strict donor screening, this technique offers a promising path to parenthood.

For expert fertility care, Dr. Apoorva Pallam Reddy provides personalized donor sperm programs, ensuring a safe and ethical approach to help individuals achieve their dream of having a child.